Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Physics of biological pattern formation]

A Gierer

    Die Naturwissenschaften
    |May 1, 1981
    PubMed
    Summary
    This summary is machine-generated.

    Genes instruct complex structure formation in organisms using morphogenetic fields. These fields, based on physical laws, guide cell responses for pattern and form development.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Quantitative analysis of cell types during growth and morphogenesis in Hydra.

    Wilhelm Roux' Archiv fur Entwicklungsmechanik der Organismen·2017
    Same author

    Model for DNA and protein interactions and the function of the operator.

    Nature·2010
    Same author

    Pattern formation by local self-activation and lateral inhibition.

    BioEssays : news and reviews in molecular, cellular and developmental biology·2000
    Same author

    Networks of gene regulation, neural development and the evolution of general capabilities, such as human empathy.

    Zeitschrift fur Naturforschung. C, Journal of biosciences·1998
    Same author

    Group report: emergent properties of natural and artificial systems.

    Zeitschrift fur Naturforschung. C, Journal of biosciences·1998
    Same author

    Possible involvement of gradients in guidance of receptor cell axons towards their target position on the olfactory bulb.

    The European journal of neuroscience·1998

    Area of Science:

    • Developmental biology
    • Biophysics
    • Systems biology

    Context:

    • Biological development involves intricate pattern and form generation.
    • Gene expression guides the formation of complex structures in higher organisms.
    • Morphogenetic fields are hypothesized to orchestrate cellular responses.

    Purpose:

    • To explain the physical and chemical mechanisms underlying biological pattern formation.
    • To demonstrate how simple molecular interactions can generate complex biological forms.
    • To account for self-regulatory properties observed in biological development.

    Summary:

    • Morphogenetic fields, likely spatial concentration patterns, elicit cell responses leading to visible patterns and form.
    • Autocatalytic short-range activation coupled with long-range inhibition can create striking concentration patterns from uniform distributions.

    Related Experiment Videos

  • Cellular responses include differentiation and the generation of mechanical forces influencing tissue morphogenesis.

    • Impact:

    • Provides a biophysical explanation for biological pattern formation based on known physical laws.
    • Suggests that complex biological structures can arise from relatively simple molecular mechanisms.
    • Offers a framework for understanding self-regulation and form generation in developmental processes.