Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Malignant hyperthermia. Considerations for the ophthalmologist

L A Sedwick, P E Romano

    Survey of Ophthalmology
    |May 1, 1981
    PubMed
    Summary

    Malignant hyperthermia is a rare, poorly understood condition causing high fever during surgery. Life-saving treatments like dantrolene sodium exist, and diagnosis is possible through muscle biopsy.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Should we be celebrating a belated silver 25th anniversary of Arthur Jampolsky's original published description of Postop' adjustable sutures in Strabismus surgery? Or not?

    Binocular vision & strabismus quarterly·2001
    Same author

    September 11; also: dexedrine or surgery for exotropia? Modified Foster; DEP or masked DVD?; You're not very good at gaze and head tilt angles; more on atropine for myopia and ARM.

    Binocular vision & strabismus quarterly·2001
    Same author

    There's no need to risk retinal light toxicity in the medical management of progressive school myopia with atropine (and photochromic bifocals). It is medically indicated.

    Binocular vision & strabismus quarterly·2001
    Same author

    Report of the meeting of the American Academy of Pediatrics Section on Ophthalmology. "Why Can't EYE Learn?'.

    Binocular vision & strabismus quarterly·2001
    Same author

    Evidence based medicine: a fad? A fraud? A tool? Good, bad or just plain evil? Hirschberg's legacy; superior oblique weakening; stiff necks; CPEO.

    Binocular vision & strabismus quarterly·2001
    Same author

    An apology. Re: Web correspondence. Binocul Vis Strabismus Q 2001; 16(1):11.

    Binocular vision & strabismus quarterly·2001

    Area of Science:

    • Anesthesiology
    • Pharmacology
    • Genetics

    Background:

    • Malignant hyperthermia (MH) is a rare, life-threatening hypermetabolic complication during anesthesia.
    • It manifests as severe hyperpyrexia (high fever) and muscle rigidity.
    • The exact pathophysiology of MH remains incompletely understood.

    Purpose of the Study:

    • To review the clinical presentation and management of malignant hyperthermia.
    • To highlight diagnostic methods and therapeutic interventions.
    • To emphasize the anesthetic risks associated with MH.

    Main Methods:

    • Review of existing literature on malignant hyperthermia.
    • Discussion of diagnostic criteria and therapeutic agents.
    • Analysis of anesthetic implications and patient risk factors.

    Main Results:

    • Malignant hyperthermia (MH) presents as operative or postoperative hyperpyrexia with a hypermetabolic state.
    • Procaine and dantrolene sodium (Dantrium) are identified as specific, life-saving therapies.
    • Diagnosis can be confirmed via muscle biopsy in patients from affected families.

    Conclusions:

    • Malignant hyperthermia is a critical consideration in all general anesthetic procedures.
    • Early recognition and prompt treatment with agents like dantrolene sodium are crucial for survival.
    • Genetic predisposition plays a role, necessitating diagnostic vigilance in at-risk individuals.

    Related Experiment Videos