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[Chronic osteomyelitis, its pathogens. Analysis of 79 cases (1978/1979) (author's transl)]
Abstract:
Pathogens and their antibiogram of 79 patients suffering from osteomyelitis were examined. Monoinfection was present in a percentage of 66. The still dominant role of Staph. aureus could be confirmed, but also the increasing number of gram-negative bacteria. The mixed infection is obviously determined by gram-negative germs with their marked resistance to antibiotics. Ps. aeruginosa was isolated as the most frequent gram-negative pathogen. On an average Gentamycin was effective in a percentage of 95. Systemic and also topic application of antibiotics should be subjected to strict rules.
Insights
This study examined osteomyelitis pathogens and antibiotic resistance in 79 patients. Gram-negative bacteria, particularly Pseudomonas aeruginosa, are increasing and show significant antibiotic resistance, necessitating strict antibiotic application rules.
Area of Science:
- Microbiology
- Infectious Diseases
- Clinical Medicine
Context:
- Osteomyelitis is a serious bone infection.
- Antibiotic resistance is a growing global health concern.
- Understanding pathogen profiles is crucial for effective treatment.
Purpose:
- To analyze the antibiogram of pathogens causing osteomyelitis.
- To identify the prevalence of different bacterial types (Staphylococcus aureus, gram-negative bacteria).
- To assess the effectiveness of Gentamycin against isolated pathogens.
Summary:
- A study of 79 osteomyelitis patients revealed monoinfection in 66% of cases.
- Staphylococcus aureus remains dominant, but gram-negative bacteria are increasing.
- Pseudomonas aeruginosa was the most frequent gram-negative pathogen, often exhibiting high antibiotic resistance.
- Gentamycin showed 95% effectiveness on average.
Impact:
- Highlights the need for updated antibiotic treatment guidelines for osteomyelitis.
- Emphasizes the challenge posed by antibiotic-resistant gram-negative bacteria.
- Suggests stricter regulations for systemic and topical antibiotic use in osteomyelitis cases.