Effect of gelatin infusion on urinary excretion of water and electrolytes in rats
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Published on: July 19, 2011
Abstract:
The effect of gelatin infusion on water and electrolyte excretion in urine was studied by measuring the volume of excreted urine and the urinary excretion of Na+, K+, Ca++ and Mg++ in a group of male rats before and after receiving infusions of a 5% autoclaved gelatin solution containing 1% glycine (1 ml/100 g body). A similar group of rats received the diluent only (control group). The results obtained showed that the diluent had a diuretic and natriuretic effect but with a less marked degree than gelatin solution which caused marked diuresis, natriuresis and increased excretion of Ca++ and Mg++ in the urine. The K+ excretion was significantly decreased following gelatin infusion. All of these measurements returned to the base-line level after 72 h following gelatin infusion.
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