The effect of suxamethonium on intraocular pressure

A method is described of measuring the elevation of the intraocular pressure (IOP) caused by suxamethonium in patients in whom other factors which may cause a change in IOP are kept constant. Use of this method confirms that suxamethonium 1 mg/kg causes a statistically significant rise in IOP which lasts for 10 minutes. A rise in IOP which is not significantly different from this is caused by suxamethonium 2.5 mg/kg, suxamethonium 1 mg/kg immediately preceded by thiopentone 3 mg/kg and by suxamethonium 1 mg/kg, 3 minutes after tubocurarine 0.1 mg/kg.