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Published on: February 6, 2011
Two-dimensional echocardiography in patients with focal cerebral ischemia
Insights
Two-dimensional echocardiography (2D echo) has limited value for detecting cardiac sources of cerebral embolization in patients with unexplained ischemic events. Its routine use is not recommended due to a low diagnostic yield in many cases.
Area of Science:
- Cardiology
- Neurology
- Medical Imaging
Background:
- Cerebral embolization is a significant cause of focal cerebral ischemia.
- Identifying a cardiac source is crucial for appropriate management and secondary prevention.
- Two-dimensional echocardiography (2D echo) is a non-invasive imaging technique used to evaluate cardiac structures.
Purpose of the Study:
- To evaluate the diagnostic utility of 2D echo in identifying cardiac sources of cerebral embolization.
- To assess the yield of 2D echo in patients with recent focal cerebral ischemia.
Main Methods:
- A study of 138 patients with recent focal cerebral ischemia was conducted.
- Patients were evaluated for suspected cardiac mechanisms or had no identified cause for ischemia.
- Two-dimensional echocardiography was performed to identify intracardiac thrombus or other cardiac disorders.
Main Results:
- Intracardiac thrombus was detected in 6.5% of patients.
- Other potentially related cardiac disorders were found in 23.2% of patients.
- 2D echo showed limited value in patients without prior cardiac disease or hypertension, but was more useful in those with known cardiac conditions like atrial fibrillation.
Conclusions:
- 2D echocardiography can identify various cardiac disorders associated with cerebral ischemia.
- The overall low diagnostic yield does not support the routine use of 2D echo in all patients with unexplained cerebral ischemic events.
- Selective use of 2D echo may be more beneficial in specific patient populations with suspected cardiac involvement.
Abstract:
To assess the use of two-dimensional (2D) echocardiography in demonstrating a cardiac source for cerebral embolization, we studied 138 patients with one or more recent episodes of focal cerebral ischemia, in whom either a cardiac mechanism was suspected or no probable mechanism of ischemia was identified. Intracardiac thrombus was found in nine patients (6.5%); 32 (23.2%) had other cardiac disorders possibly related to the ischemia; and the remaining 97 (70.3%) had study results that were normal or added nothing to the clinical findings. Thus, 2D echocardiography was of limited value in patients with no clinical cardiac disease or hypertension only, and of greater value in patients with known cardiac disease, especially atrial fibrillation. Although 2D echocardiography can demonstrate a wide range of disorders that may be associated with ischemia, the overall low yield does not warrant routine use of this study in all patients with unexplained cerebral ischemic events.
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