Peripheral corneal infiltrates in inflammatory bowel disease

Two patients with ulcerative colitis and one patient with Crohn's disease developed unilateral corneal lesions. There were small white peripheral subepithelial infiltrates associated with mild irritative symptoms. No signs of staphylococcal infection were present, and the intestinal disease was inactive. The corneal lesions cleared rapidly with topical corticosteroids or systemic indomethacin.