Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Multiple virus vaccines and the interference phenomena]

L Dardanoni

    Annali Sclavo; Rivista Di Microbiologia E Di Immunologia
    |January 1, 1980
    PubMed
    Summary

    Viral interference, where one virus prevents another from infecting, is a known phenomenon. This study explores why this interference doesn't typically occur with combined attenuated virus vaccines, ensuring their effectiveness.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Familial aggregation of tumors and detection of hereditary non-polyposis colorectal cancer in 3-year experience of 2 population-based colorectal-cancer registries.

    International journal of cancer·1995
    Same author

    Cancers of the female genital tract in Ragusa, Sicily.

    European journal of epidemiology·1995
    Same author

    [Analysis of the quality of death certificates for neoplasms in the province of Ragusa].

    Epidemiologia e prevenzione·1992
    Same author

    Risk factors of nonmelanoma skin cancer in Ragusa, Sicily: a case-control study.

    Cancer causes & control : CCC·1991
    Same author

    Epidemiological aspects of hepatitis B in Palermo: changes in HBV spread.

    European journal of epidemiology·1991
    Same author

    [Diseases caused by microbes].

    Epidemiologia e prevenzione·1991

    Area of Science:

    • Virology
    • Immunology
    • Vaccinology

    Context:

    • Simultaneous viral infections can lead to interference, potentially excluding one virus.
    • Attenuated virus vaccines are increasingly administered in combination (e.g., trivalent polio, mumps-measles-rubella).
    • The effectiveness of combined attenuated virus vaccines is well-established.

    Purpose:

    • To theoretically consider the implications of viral interference in the context of immunization.
    • To investigate the reasons behind the non-operativity of viral interference in combined attenuated virus vaccines.

    Summary:

    • Viral interference is a known biological phenomenon where coinfecting viruses compete, potentially leading to the exclusion of one.
    • Despite this, combined attenuated virus vaccines, such as those for polio or mumps, measles, and rubella, are effective.
    • This suggests that the interference mechanism is generally non-operative under the conditions of combined attenuated virus vaccination.

    Impact:

    • Provides a theoretical framework for understanding vaccine efficacy when multiple attenuated viruses are administered together.
    • Supports the continued development and use of multi-component vaccines.
    • Highlights the importance of considering viral dynamics in vaccine design and application.

    Related Experiment Videos