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Pancreatic pseudocysts. A follow-up study

A Bødker, J Kjaergaard, A Schmidt

    Annals of Surgery
    |July 1, 1981
    PubMed
    Summary
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    Pancreatic pseudocyst surgery outcomes were poorer for alcoholics who continued drinking. Abstinence or non-alcoholic causes correlated with better long-term results and less pain.

    Area of Science:

    • Gastroenterology
    • Surgical Oncology
    • Hepatobiliary Surgery

    Background:

    • Pancreatic pseudocysts are a significant complication, often linked to alcohol abuse.
    • Surgical intervention is necessary for managing symptomatic or complicated pseudocysts.
    • Understanding long-term outcomes is crucial for patient management.

    Purpose of the Study:

    • To evaluate the surgical outcomes and long-term results of patients treated for pancreatic pseudocysts.
    • To identify factors influencing patient prognosis, particularly alcohol consumption.

    Main Methods:

    • Retrospective analysis of 37 men and 14 women operated on for pancreatic pseudocysts between 1968 and 1978.
    • Data collected included patient demographics, etiology, surgical procedure, hospital mortality, and long-term follow-up.

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  • Patients were categorized by surgical approach: internal drainage, external drainage, and pancreatic resection.
  • Main Results:

    • Alcohol abuse was the primary cause in 65% of cases.
    • Hospital mortality was 14%, with older patients having higher mortality.
    • Long-term follow-up (median 4 years) revealed a further 13% mortality.
    • Severe pain at follow-up was reported by 30% of alcoholics versus 0% of non-alcoholics.
    • Continued alcohol consumption correlated with poorer work ability and increased pain.

    Conclusions:

    • Surgical management of pancreatic pseudocysts has significant associated mortality.
    • Alcohol abuse is a major risk factor for pancreatic pseudocyst development and poorer long-term outcomes.
    • Patient outcomes are significantly better for non-alcoholics and alcoholics who achieve abstinence.