[Significance of serum alkaline phosphatase in secondary hepatic localizations (author's transl)]

The Authors analysed 292 patients with tumours particularly liable to hepatic metastatization, excluding from a wider set of cases all those which on grounds of age, bone localisations and other kinds of hepatic disease might have falsified the serum A. Ph. values. Analysis of their results led to exclusion of any direct relationship between hyperphosphatemia and degree of hepatic metastatization. It is also concluded that pathological observation of this enzyme, in the absence of semeiological data indicating secondary hepatic pathology, must be considered as grounds for fuller diagnostic investigation.