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Lead systems for internal ventricular fibrillation

G M Deeb, B P Griffith, M E Thompson

    Circulation
    |August 1, 1981
    PubMed
    Summary
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    This study assessed implantable defibrillators, finding lead systems effective for internal defibrillation. Defibrillation thresholds remained stable, supporting their use in devices delivering 20-35 J.

    Area of Science:

    • Biomedical Engineering
    • Cardiovascular Research

    Background:

    • Ventricular fibrillation poses a significant risk.
    • Automatic implantable defibrillators (AIDs) offer a potential solution.
    • Establishing effective internal defibrillation thresholds is crucial for AID development.

    Purpose of the Study:

    • To evaluate the feasibility of a standby automatic implantable defibrillator.
    • To determine the defibrillation thresholds for two distinct lead systems.
    • To assess the long-term stability of these thresholds.

    Main Methods:

    • Two lead systems (pericardial patches and transvenous catheter) were investigated.
    • Implantation was performed in dogs (thoracotomy) and pigs (subxiphoid approach).
    • Defibrillation thresholds were measured periodically over 54 weeks in dogs and at 6 weeks in pigs.

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    Main Results:

    • Defibrillation thresholds were consistently satisfactory for both lead systems in both species.
    • In dogs, the mean defibrillation threshold for System I was 10.5 J at 4 weeks and showed no significant change over 54 weeks.
    • Thresholds in pigs at 6 weeks were comparable, indicating stable performance.

    Conclusions:

    • Both investigated lead systems are feasible for use in implantable defibrillators.
    • The established defibrillation thresholds are suitable for devices delivering 20-35 J.
    • The findings support the development and clinical application of standby automatic implantable defibrillators.