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Exercise-induced asthma in Nepalese children

C R Bangham, R A Hope

    Clinical Allergy
    |May 1, 1981
    PubMed
    Summary
    This summary is machine-generated.

    This study in Nepal found asthma in six children (2%) aged 5-15. None of the diagnosed asthma cases were positive on skin prick tests, suggesting alternative diagnostic approaches are needed.

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    Area of Science:

    • Pediatric Respiratory Medicine
    • Epidemiology
    • Allergy and Immunology

    Background:

    • Asthma and atopy prevalence studies are crucial for understanding respiratory health in diverse populations.
    • Limited data exists on childhood asthma and atopy in the specific context of rural Nepal.

    Purpose of the Study:

    • To determine the prevalence of asthma and atopy in children aged 5-15 in rural East Nepal.
    • To identify the primary causes and diagnostic indicators of asthma in this population.
    • To establish normal reference values for peak expiratory flow rate (PEFR) and exercise-induced changes.

    Main Methods:

    • A study population of 301 children (5-15 years) was recruited from East Nepal.
    • Asthma diagnosis utilized medical history, clinical examination, and a 6-minute exercise (step) test.

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  • Skin prick tests were performed, with results detailed in a separate publication.

    • Main Results:

    • Asthma was diagnosed in 6 children (1.99% prevalence).
    • None of the children diagnosed with asthma showed positive results on skin prick tests.
    • Baseline and exercise-induced peak expiratory flow rate (PEFR) values were recorded for various groups.

    Conclusions:

    • The study highlights a low prevalence of asthma in this specific Nepalese pediatric cohort.
    • The lack of positive skin prick tests in diagnosed asthmatics suggests potential limitations of this diagnostic method in this population.
    • Establishing normative PEFR data is valuable for future respiratory health assessments in children.