[Experimental liver arterialization following portacaval shunt - rehabilitation]

Comparative investigations were carried out on rats with healthy livers and rats with thioacetamide-cirrhotic livers on postoperative days 2 and 21 following end-to-side portacaval anastomosis alone and with additional (documented) flow-limited arterialization of the portal stump. After portacaval anastomosis alone, all the parameters investigated (biochemical, pharmacokinetic, and morphological) were impaired. By means of the additional flow-limited arterialization, the disadvantages can be greatly headed off, more clearly in healthy than in cirrhotic animals.