[Comparative study of the electrophoretic mobility of erythrocytes and erythrocyte "ghosts" isolated form rats]

Electrophoretic mobilities of rat erythrocytes and their "ghosts" are investigated. It is that the registered figures for the electrophoretic mobilities for echinocytes and discocytes are due to their specific molecular arrangements and different charge distribution topology. The reduction of the mobilities registered for the "ghosts" compared with native erythrocytes, probably, is caused by the interactions between different species of integral peripheral membrane proteins while the "ghosts" are isolated. The redistribution of the surface charge, accompanying this process, leads to unfolding of the cytoskeleton and increase of internal resistance of the suspending media. As a result a reduction of the electrophoretic mobilities for "ghost" preparations is occurred.