Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Computer-controlled radiation therapy

M B Levene, P K Kijewski, L M Chin

    Radiology
    |December 1, 1978
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Search for contact interactions and large extra dimensions in the dilepton channel using proton-proton collisions at [Formula: see text] 8 TeV with the ATLAS detector.

    The European physical journal. C, Particles and fields·2015
    Same author

    Search for Scalar Charm Quark Pair Production in pp Collisions at sqrt[s]=8  TeV with the ATLAS Detector.

    Physical review letters·2015
    Same author

    Search for [Formula: see text] decays in [Formula: see text] collisions at [Formula: see text] = 8 TeV with the ATLAS detector.

    The European physical journal. C, Particles and fields·2015
    Same author

    Measurement of spin correlation in top-antitop quark events and search for top squark pair production in pp collisions at √s=8  TeV using the ATLAS detector.

    Physical review letters·2015
    Same author

    Measurement of the inclusive jet cross-section in <i>pp</i> collisions at [Formula: see text] and comparison to the inclusive jet cross-section at [Formula: see text] using the ATLAS detector.

    The European physical journal. C, Particles and fields·2015
    Same author

    Search for Higgs and Z Boson Decays to J/ψγ and ϒ(nS)γ with the ATLAS Detector.

    Physical review letters·2015
    Same journal

    Erratum for: Prediction of Lobar Emphysema Progression with a CT-Based Foundational Model.

    Radiology·2026
    Same journal

    Erratum for: Associations of MRI-derived Paraspinal IMAT and LMM with Cardiometabolic Risk Factors: Results from a German Cohort.

    Radiology·2026
    Same journal

    Erratum for: Blue Rubber Bleb Nevus Syndrome.

    Radiology·2026
    Same journal

    Redefining the Clinical Role of MRI in Endometrial Cancer Staging.

    Radiology·2026
    Same journal

    To Ablate or Not to Ablate: The Colorectal Liver Metastasis Question.

    Radiology·2026
    Same journal

    The Limits of Radiologic Categorization in Pulmonary Nonsolid Nodules.

    Radiology·2026
    See all related articles

    Computer-controlled radiation therapy uses advanced equipment to improve radiation dose distributions, overcoming limitations posed by sensitive normal tissues. This technique offers enhanced local control for cancer treatment.

    Area of Science:

    • Medical Physics
    • Radiation Oncology
    • Computer Science

    Background:

    • Radiation therapy effectiveness is often limited by the need to irradiate through sensitive normal tissues, acting as dose-limiting barriers.
    • Protecting healthy tissues while maximizing tumor dose is a critical challenge in radiation oncology.

    Purpose of the Study:

    • To introduce and evaluate a computer-controlled radiation therapy system for improved dose distribution.
    • To explore the potential for enhanced local tumor control by optimizing radiation delivery.

    Main Methods:

    • Utilized a Mevatron XII linear accelerator, retrofitted for automatic computer control.
    • Employed a PDP 11/45 minicomputer to manage treatment parameter variations during irradiation.
    • Demonstrated dose distributions achievable with the new system.

    Related Experiment Videos

    Main Results:

    • Achieved improved radiation dose distributions compared to conventional methods.
    • Showcased the capability of simultaneous variation of multiple treatment parameters.
    • Presented dose distributions illustrating the system's potential.

    Conclusions:

    • Computer-controlled radiation therapy offers a promising approach to overcome normal tissue dose limitations.
    • The developed system has the potential to improve local control in radiation oncology.
    • Further clinical investigation is warranted to fully assess the benefits.