Related Experiment Video

Updated: Aug 19, 2026

Isolation and Functional Characterization of Human Ventricular Cardiomyocytes from Fresh Surgical Samples
14:39

Isolation and Functional Characterization of Human Ventricular Cardiomyocytes from Fresh Surgical Samples

Published on: April 21, 2014

[Accelerated idioventricular rhythm wih isorhythmic A-V dissociation. An electrophysiological study (author's

P Delise, D D'Este, E Monico

    Giornale Italiano Di Cardiologia
    |January 1, 1980
    PubMed

    Insights

    Accelerated idioventricular rhythm with isorhythmic A-V dissociation can persist for months. Electrophysiological studies show the focus is in the conduction system, suggesting increased firing of normal pacemakers.

    Area of Science:

    • Cardiology
    • Electrophysiology

    Background:

    • Accelerated idioventricular rhythm (AIVR) is a ventricular arrhythmia.
    • Isorhythmic atrioventricular (A-V) dissociation can occur with AIVR.

    Observation:

    • Presents three cases of AIVR with isorhythmic A-V dissociation.
    • One patient had hypertrophic non-obstructive cardiomyopathy; two had coronary heart disease with prior myocardial infarction.
    • Arrhythmia persisted for days to months in all cases.

    Findings:

    • Electrophysiological studies revealed the focus was not protected by entrance block.
    • The arrhythmia focus was localized to the main branches of the conduction system: right bundle branch in one case, and anterior/posterior fascicles of the left bundle branch in the others.
    • These findings suggest AIVR results from increased firing of normal idioventricular pacemakers.

    Implications:

    • The term 'accelerated idioventricular rhythm' is preferred over 'slow ventricular tachycardia' for this specific electrogenetic mechanism.
    • Understanding the precise localization and electrogenesis of AIVR is crucial for accurate diagnosis and management.
    • This study contributes to the understanding of ventricular arrhythmias in patients with underlying cardiac conditions.

    More Related Videos

    Ablation of Ischemic Ventricular Tachycardia Using a Multipolar Catheter and 3-dimensional Mapping System for High-density Electro-anatomical Reconstruction06:57

    Ablation of Ischemic Ventricular Tachycardia Using a Multipolar Catheter and 3-dimensional Mapping System for High-density Electro-anatomical Reconstruction

    Published on: January 31, 2019

    Dual-Dye Optical Mapping of Hearts from RyR2R2474S Knock-In Mice of Catecholaminergic Polymorphic Ventricular Tachycardia09:36

    Dual-Dye Optical Mapping of Hearts from RyR2R2474S Knock-In Mice of Catecholaminergic Polymorphic Ventricular Tachycardia

    Published on: December 22, 2023

    Related Concept Videos

    Electrophysiology of Normal Cardiac Rhythm01:19

    Electrophysiology of Normal Cardiac Rhythm

    The normal cardiac rhythm is a synchronized electrical activity that facilitates the regular and coordinated contraction of the heart muscle. This process is essential for efficient blood circulation throughout the body. The fundamental elements involved in establishing and maintaining this rhythm include the unique electrical properties of cardiac muscle cells, the sinoatrial (SA) node's pacemaker function, the specialized conducting system, and the ionic mechanisms underlying each phase of...
    Disturbances in Heart Rhythm01:29

    Disturbances in Heart Rhythm

    Arrhythmia or dysrhythmia refers to an abnormal heart rhythm caused by a defect in the heart's conduction system. It can cause the heart to beat irregularly, too quickly, or too slowly, leading to symptoms like chest pain, shortness of breath, and fainting. Factors such as stress, caffeine, alcohol, nicotine, cocaine, certain drugs, congenital defects, diseases, and electrolyte abnormalities can trigger arrhythmias.
    Arrhythmias are categorized by their speed, rhythm, and origin. A slow heart...
    Dysrhythmias III: Characteristics of Dysrhythmias01:29

    Dysrhythmias III: Characteristics of Dysrhythmias

    Dysrhythmias, also known as arrhythmias, are irregular heart rhythms that result from abnormal electrical activity in the heart, affecting its ability to circulate blood efficiently. Tachyarrhythmias, a subset of dysrhythmias, are characterized by abnormally fast heart rates exceeding 100 beats per minute. Here are some types of tachyarrhythmias with their distinct ECG features:Sinus Tachycardia:Sinus tachycardia presents a regular heart rhythm with an increased rate of 101-180 beats per minute.
    Dysrhythmias IV: Characteristics of Bradyarrhythmias01:18

    Dysrhythmias IV: Characteristics of Bradyarrhythmias

    Bradyarrhythmias are cardiac rhythm disorders characterized by a slower-than-normal heart rate, typically defined as fewer than 60 beats per minute. Some of which are discussed here:Sinus BradycardiaSinus bradycardia presents a heart rate lower than 60 beats per minute, with a regular rhythm originating from the SA node. The ECG typically shows normal P waves preceding each QRS complex, a normal PR interval (0.12 to 0.20 seconds), and a normal QRS duration (0.06 to 0.10 seconds).First-Degree AV...
    Dysrhythmias V: Evaluating Dysrhythmias01:30

    Dysrhythmias V: Evaluating Dysrhythmias

    Dysrhythmias, also known as arrhythmias, are disturbances in the heart's rhythm that range from benign to life-threatening. A thorough evaluation is crucial for appropriate management and involves a comprehensive medical history, physical examination, and various diagnostic tests.Medical HistorySymptoms: Collect detailed information on palpitations, dizziness, syncope, chest pain, and fatigue. Note their onset, frequency, and triggers.Previous Cardiac Issues: Document any history of heart...