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Updated: Aug 16, 2026

Cell-free Biochemical Fluorometric Enzymatic Assay for High-throughput Measurement of Lipid Peroxidation in High Density Lipoprotein
Published on: October 12, 2017
[High-density lipoproteins in children with coronary diseases]
Abstract:
Low HDL-cholesterol and increased LDL-cholesterol have been shown to be cardiovascular risk factors. Recently, HDL/serum cholesterol and HDL/ LDL-cholesterol ratios have been advocated as more reliable indices of cardiovascular risk factors. In a comparative study, lipoprotein-cholesterol and lipoproteins-triglycerides as well as the HDL/serum cholesterol and HDL/LDL-cholesterol ratios were determined in children of patients with coronary heart disease (CHD) and in healthy control children. Sons of CHD patients had significantly lower HDL-cholesterol and HDL/LDL-cholesterol ratios than controls. In daughters, the HDL-cholesterol and HDL/LDL ratio were also decreased reaching significance in HDL only in the 12 to 16 year age group. Under comparative environmental situations, the results suggest that low HDL-cholesterol in children of CHD patients could be genetically determined.
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