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Related Experiment Videos

Ochronotic stenosing flexor tenosynovitis--case report

H Seradge

    The Journal of Hand Surgery
    |July 1, 1981
    PubMed
    Summary

    Ochronotic pigment deposition in the flexor digitorum profundus tendons can cause triggering of the fingers. Repetitive trauma may enhance this localized pigment accumulation, leading to symptoms.

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    Area of Science:

    • Orthopedics
    • Histopathology
    • Rheumatology

    Background:

    • Ochronosis is a rare metabolic disorder characterized by the deposition of homogentisic acid pigment in connective tissues.
    • Tendinous involvement in ochronosis is uncommon, with limited understanding of its pathogenesis.

    Observation:

    • A case study identified localized ochronotic pigment deposition within the flexor digitorum profundus tendons.
    • This deposition was clinically associated with triggering of the affected fingers.

    Findings:

    • Histologic examination confirmed the presence of ochronotic pigment within the tendon tissue.
    • The study suggests repetitive microtrauma may play a significant role in initiating localized pigment deposition in the flexor tendons.

    Implications:

    • Understanding the role of trauma in ochronotic tenopathy may inform preventative strategies.
    • Further research into the biomechanics of ochronotic pigment deposition in tendons is warranted.
    • This case highlights a potential, previously under-recognized, cause of tendinopathy in patients with ochronosis.

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