Adverse reactions to simultaneous influenza and pneumococcal vaccination

The perceptions of 202 patients who were given either influenza vaccine (n = 68), pneumococcal vaccine (n = 45), or both (n = 95) as to local and systemic toxicity are compared. Pneumococcal vaccination and simultaneous vaccination caused a minimally greater frequency and severity of side effects compared to influenza vaccination. Simultaneous vaccination for influenza and pneumococcal pneumonia appears to be safe.