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Updated: Jul 26, 2026
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Psychophysical Tracking Method to Measure Taste Preferences in Children and Adults
Published on: July 16, 2016
The Sweet syndrome in children
The Journal of Pediatrics
|July 1, 1981
Summary
Sweet syndrome, a rare neutrophilic dermatosis, typically affects middle-aged women but was observed in two children. Symptoms include fever, high white blood cell count, and painful skin lesions, resolving with corticosteroids.
Area of Science:
- Dermatology
- Pediatrics
- Rheumatology
Background:
- Sweet syndrome, or acute febrile neutrophilic dermatosis, is a rare inflammatory condition.
- It predominantly affects middle-aged women, making pediatric cases unusual.
Observation:
- Two pediatric cases of Sweet syndrome are presented.
- Clinical presentation included high fever, neutrophilic leukocytosis, and characteristic painful, erythematous skin plaques and nodules.
Findings:
- Histopathological examination revealed a dense dermal infiltrate of polymorphonuclear leukocytes.
- The condition demonstrated rapid resolution following systemic corticosteroid administration.
Implications:
- This case series expands the known demographic of Sweet syndrome to include children.
- It highlights the importance of considering Sweet syndrome in pediatric patients presenting with fever and specific dermatological manifestations.
- The findings underscore the hypersensitivity reaction hypothesis, potentially triggered by infection or malignancy, in the pathogenesis of Sweet syndrome.
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