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Blood pressure changes resulting from aortography

S L Snowdon, G H Whitehouse

Journal of the Royal Society of Medicine

|June 1, 1981

Summary

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Conventional ionic contrast media cause significant hypotension in patients with arteriosclerosis undergoing aortography. Non-ionic contrast media, like metrizamide, result in less severe and shorter-lasting blood pressure drops.

Area of Science:

Cardiovascular medicine
Radiology
Pharmacology

Background:

Patients undergoing aortography often have generalized arteriosclerosis.
Uncontrolled hypotension is a significant risk, particularly with myocardial depression.

Purpose of the Study:

To compare the hemodynamic effects of conventional ionic contrast media versus a non-ionic contrast medium during aortography.

Main Methods:

Patients received conventional ionic contrast media (Urografin 370, Cardioconray) or metrizamide (non-ionic).
Blood pressure changes and duration of hypotension were monitored after each injection.

Main Results:

Conventional ionic contrast media caused significant hypotension in all patients.

Related Experiment Videos

Metrizamide was associated with a less pronounced and shorter duration of blood pressure decrease.

Conclusions:

Non-ionic contrast media, such as metrizamide, offer a safer alternative to ionic media for aortography in patients with arteriosclerosis due to reduced hypotensive effects.