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[Mechanisms of the development of hypercoagulation in experimental peroxide atherosclerosis]

V P Mishchenko, L L Goncharenko, V N Bobryrev

|April 1, 1981

Abstract:

It is shown that atheroarteriosclerosis develops with attendant hypercoagulation changes in the blood of animals kept on an antioxidant-free diet for 100 days. The changes in blood coagulation are caused by disturbances in the procoagulant properties of the tissue (heart and aorta) cell membranes and those of the red cells. The role of cell membranes in the development of hypercoagulation due to changes in their cell thromboplastic properties is discussed.

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