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[Computed tomography in multiple sclerosis]

F Mikol, A Bouchareine, M L Aubin

    Revue Neurologique
    |January 1, 1980
    PubMed
    Summary
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    Computed tomography (CT) scans reveal abnormal brain changes in most multiple sclerosis patients. These CT findings, while not specific, aid in diagnosing multiple sclerosis and monitoring active lesions.

    Area of Science:

    • Neurology
    • Radiology

    Background:

    • Multiple sclerosis (MS) is a chronic neurological disease affecting the central nervous system.
    • Accurate diagnostic tools are crucial for managing MS and understanding disease progression.

    Purpose of the Study:

    • To evaluate the utility of computed tomography (CT) in diagnosing multiple sclerosis (MS).
    • To correlate CT findings with clinical presentation and disease activity in MS patients.

    Main Methods:

    • Sixty patients diagnosed with multiple sclerosis underwent computed tomography (CT) scans.
    • Iodine contrast medium was administered to 48 patients; 6 patients had follow-up scans.
    • Analysis focused on image density, cerebral atrophy, and mass effect.

    Main Results:

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    • Abnormal CT readings were observed in 75% of patients.
    • Findings included increased density (10 patients), reduced density (10 patients), and cerebral atrophy (26 patients).
    • Increased densities, often seen during acute episodes, tended to normalize over time.

    Conclusions:

    • CT findings, including density changes and atrophy, support the diagnosis of multiple sclerosis when considered collectively.
    • The absence of mass effect and correlation with clinical signs are key diagnostic indicators.
    • Regions of increased density may represent active demyelination, valuable for long-term patient monitoring.