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Is the enuretic female bladder without instability normal?

J R Hindmarsh, P O Byrne

    Urological Research
    |January 1, 1981
    PubMed
    Summary
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    Nocturnal enuresis in females is linked to bladder/urethral dysfunction. Stable bladders showed abnormalities in 19 of 21 cases, suggesting dual causes for bedwetting.

    Area of Science:

    • Urology
    • Pediatric Urology
    • Nephrology

    Background:

    • Nocturnal enuresis (bedwetting) affects many individuals, particularly females.
    • Previous theories suggest a combination of factors contribute to its development.
    • Understanding bladder and urethral function is crucial for effective treatment.

    Purpose of the Study:

    • To investigate bladder and urethral function in females with nocturnal enuresis.
    • To identify specific functional abnormalities associated with persistent bedwetting.
    • To evaluate the role of detrusor stability and bladder capacity in nocturnal enuresis.

    Main Methods:

    • Cystometric testing was performed on 21 female patients with a history of nocturnal enuresis.
    • Detrusor stability was assessed using provocative maneuvers including rapid filling, standing, coughing, and erect filling.

    Related Experiment Videos

  • A comprehensive evaluation of 10 specific bladder/urethral measurements was conducted.
  • Main Results:

    • All 21 participants exhibited stable bladders on cystometric testing.
    • Despite bladder stability, 19 out of 21 patients (90.5%) demonstrated abnormalities in detailed functional assessments.
    • Identified abnormalities included small functional bladder capacity, outlet obstruction, increased detrusor contractility, and low urethral closure pressure.

    Conclusions:

    • The findings support a two-component theory for nocturnal enuresis: failure to arouse from sleep and a coexisting bladder/urethral functional abnormality.
    • Bladder/urethral dysfunction is a significant factor in nocturnal enuresis, even with a stable detrusor.
    • Specific identifiable causes like reduced bladder capacity and outlet issues warrant targeted therapeutic approaches.