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Related Experiment Videos

Computed tomography in herpes simplex encephalitis

J S Leo, R L Weiner, J P Lin

    Surgical Neurology
    |November 1, 1978
    PubMed
    Summary
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    Computed tomography (CT) scans reveal abnormalities in most herpes simplex encephalitis cases. Early lucency on CT scans, appearing within 48 hours, aids diagnosis and treatment.

    Area of Science:

    • Neurology
    • Radiology
    • Infectious Diseases

    Background:

    • Herpes simplex encephalitis (HSE) is a severe neurological condition.
    • Early diagnosis and treatment are crucial for patient outcomes.
    • Computed tomography (CT) is a key neuroimaging modality.

    Observation:

    • Review of 15 CT scans from nine patients with suspected HSE.
    • Analysis focused on abnormalities including lucency, mass effect, and contrast enhancement.
    • Assessment of CT findings in relation to symptom onset.

    Findings:

    • Majority of HSE cases exhibited CT abnormalities.
    • Lucency was observed in 63% of evaluable scans (5/8).
    • Mass effect (50%) and abnormal contrast enhancement (57%) were also common.

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    Implications:

    • CT scan findings support the diagnosis of HSE.
    • CT imaging helps identify optimal sites for brain biopsy.
    • Early CT detection facilitates timely treatment with antiviral agents like adenine arabinoside.