Related Experiment Video

Updated: Jul 28, 2026

Measuring Cation Transport by Na,K- and H,K-ATPase in Xenopus Oocytes by Atomic Absorption Spectrophotometry: An Alternative to Radioisotope Assays
12:48

Measuring Cation Transport by Na,K- and H,K-ATPase in Xenopus Oocytes by Atomic Absorption Spectrophotometry: An Alternative to Radioisotope Assays

Published on: February 19, 2013

[Compartment analysis of potassium metabolism--mathematical modelling of 42-K tracer kinetics]

J Neumann, P W Wüstenberg, G Esther

    Zeitschrift Fur Die Gesamte Innere Medizin Und Ihre Grenzgebiete
    |March 15, 1981
    PubMed

    Keywords:
    potassium balance diagnosticscompartment analysis methods42-K tracer applicationsmetabolic potassium disorders

    More Related Videos

    Measuring Fluxes of Mineral Nutrients and Toxicants in Plants with Radioactive Tracers13:14

    Measuring Fluxes of Mineral Nutrients and Toxicants in Plants with Radioactive Tracers

    Published on: August 22, 2014

    Quantitative [18F]-Naf-PET-MRI Analysis for the Evaluation of Dynamic Bone Turnover in a Patient with Facetogenic Low Back Pain06:31

    Quantitative [18F]-Naf-PET-MRI Analysis for the Evaluation of Dynamic Bone Turnover in a Patient with Facetogenic Low Back Pain

    Published on: August 8, 2019

    Related Concept Videos

    Compartment Models: Two-Compartment Model01:20

    Compartment Models: Two-Compartment Model

    The two-compartment model divides the body into central and peripheral compartments to account for varying blood perfusion rates among organs and tissues, affecting drug distribution. The central compartment includes blood and highly perfused tissues with rapid drug distribution, while the peripheral compartment contains tissues with slower drug distribution. After a single IV bolus dose, the drug concentration is high in plasma and low in tissues. The drug distribution between compartments...
    Model Approaches for Pharmacokinetic Data: Compartment Models01:14

    Model Approaches for Pharmacokinetic Data: Compartment Models

    Compartmental analysis is a widely adopted approach to characterizing drug pharmacokinetics. It uses compartment models that conceptualize the body as a collection of reversibly communicating compartments, each representing a group of tissues exhibiting similar drug distribution characteristics. The movement rate of the drug between these compartments is typically described by first-order kinetics.
    Two primary types of compartment models are recognized: mammillary and catenary. The more...
    One-Compartment Open Model: Wagner-Nelson and Loo Riegelman Method for ka Estimation01:24

    One-Compartment Open Model: Wagner-Nelson and Loo Riegelman Method for ka Estimation

    This lesson introduces two critical methods in pharmacokinetics, the Wagner-Nelson and Loo-Riegelman methods, used for estimating the absorption rate constant (ka) for drugs administered via non-intravenous routes. The Wagner-Nelson method relates ka to the plasma concentration derived from the slope of a semilog percent unabsorbed time plot. However, it is limited to drugs with one-compartment kinetics and can be impacted by factors like gastrointestinal motility or enzymatic degradation.
    On...
    Two-Compartment Open Model: IV Bolus Administration01:18

    Two-Compartment Open Model: IV Bolus Administration

    The two-compartment model for intravenous (IV) bolus administration illustrates drug distribution in the body, subdividing it into central and peripheral compartments. This model operates on the concept of two-compartment kinetics. The drug's plasma concentration shows a bi-exponential decline following IV bolus administration, signaling the presence of two disposition processes: distribution and elimination.
    The disparity between drug input and the sum of drug transfer rates between...
    Two-Compartment Open Model: Extravascular Administration01:12

    Two-Compartment Open Model: Extravascular Administration

    The two-compartment model for extravascular administration represents a drug's absorption and distribution process. It features a central compartment, where the drug is first absorbed, and a peripheral compartment, which illustrates the drug's distribution throughout the body. The rate of change in drug concentration in the central compartment is calculated by three exponents: absorption, distribution, and elimination.
    The absorption exponent (ka) indicates the speed at which the drug is...
    Pharmacokinetic Models: Comparison and Selection Criterion01:26

    Pharmacokinetic Models: Comparison and Selection Criterion

    Physiological and compartmental models are valuable tools used in studying biological systems. These models rely on differential equations to maintain mass balance within the system, ensuring an accurate representation of the dynamic processes at play.
    Physiological models take a detailed approach by considering specific molecular processes. They can predict drug distribution, metabolism, and elimination changes, providing a comprehensive understanding of how drugs interact with the body.