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[Advanced basal cell carcinoma]

R R Olbrisch, W Mühlbauer

    Zeitschrift Fur Plastische Chirurgie
    |June 1, 1981
    PubMed
    Summary
    This summary is machine-generated.

    Advanced basal cell carcinoma (BCC) can progress to squamous cell carcinoma (SCC), leading to limited reconstruction options and poor outcomes. Delayed treatment of BCC increases the risk of SCC development and widespread metastasis.

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    Area of Science:

    • Oncology
    • Dermatology
    • Plastic Surgery

    Context:

    • Advanced basal cell carcinoma (BCC) poses significant treatment challenges.
    • Delayed diagnosis or inadequate treatment of BCC can lead to secondary malignancies.
    • Reconstructive surgery for extensive facial defects requires careful planning.

    Purpose:

    • To analyze the outcomes of extensive plastic surgery for advanced basal cell carcinoma.
    • To investigate the incidence and consequences of squamous cell carcinoma supervening on BCC.
    • To evaluate the limitations of reconstruction and the use of prostheses in complex cases.

    Summary:

    • 306 patients with advanced BCC underwent extensive plastic surgery over five years.
    • In 12 patients, squamous cell carcinoma (SCC) developed due to delayed presentation or inadequate treatment.

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  • Reconstruction was severely limited or impossible in SCC cases, with prostheses used for defect masking. Infiltrative SCC growth towards the brain was uncontrollable, leading to systemic metastases in all 12 patients.

    • Impact:

    • Highlights the critical importance of timely and adequate treatment for basal cell carcinoma.
    • Underscores the challenges in managing advanced skin cancers and their sequelae.
    • Emphasizes the limitations of surgical reconstruction when aggressive tumors are involved.
    • Suggests a need for improved therapeutic strategies to prevent progression and metastasis of skin cancers.