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[Pharmaceutical preparations which contain tartrazine]

E Alvarez Cuesta, R Alcover Sánchez, T Sainz Martín

    Allergologia Et Immunopathologia
    |January 1, 1981
    PubMed
    Summary

    Food color additives, like tartrazine, can cause allergic reactions including hives and asthma. Many medications may contain these dyes, posing risks to allergic individuals.

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    Allergy·1992

    Area of Science:

    • Food science and toxicology
    • Clinical immunology and allergy

    Context:

    • Allergic reactions to food colorings have been documented since 1958.
    • Tartrazine (Yellow No. 5) is a common food dye known to trigger various adverse reactions.
    • Cross-reactivity between tartrazine and anti-inflammatory drugs like aspirin is observed in sensitive patients.

    Purpose:

    • To identify medications potentially containing food dyes, specifically tartrazine.
    • To assess the prevalence of food dye use in pharmaceutical products.
    • To raise awareness about the risks associated with food dye allergies in medications.

    Summary:

    • A survey of 233 laboratories revealed that 72 (45%) confirmed the presence of food dyes, including tartrazine, in certain drugs.
    • Reactions to tartrazine can range from mild pruritus to severe asthma attacks and purpura, occurring within minutes to hours.
    • The study highlights the critical issue of undeclared food dyes in medications, which can be life-threatening for allergic individuals.

    Impact:

    • Informs healthcare professionals and patients about potential allergens in medications.
    • Emphasizes the need for clear labeling of food dyes in pharmaceutical products.
    • Contributes to patient safety by reducing the risk of accidental allergic reactions to medications.

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