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Related Experiment Videos

Multiple hyperbaric exposures during pregnancy in sheep

M J Nemiroff, J R Willson, T H Kirschbaum

    American Journal of Obstetrics and Gynecology
    |July 15, 1981
    PubMed
    Summary

    Hyperbaric exposure during sheep pregnancy showed maternal bubble formation but no fetal bubbles. Most lambs were born healthy, indicating potential safety for fetal circulation during such dives.

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    Area of Science:

    • Veterinary Medicine
    • Physiology
    • Hyperbaric Medicine

    Background:

    • Hyperbaric oxygen therapy (HBOT) involves breathing pure oxygen in a pressurized chamber.
    • Understanding the effects of hyperbaric conditions on pregnancy is crucial for both human and animal health.
    • Previous research on hyperbaric exposure during gestation is limited, especially concerning fetal circulatory responses.

    Purpose of the Study:

    • To investigate the incidence of bubble formation in maternal and fetal circulations of sheep during hyperbaric exposure.
    • To assess the impact of hyperbaric dives on pregnancy outcomes and fetal well-being in sheep.

    Main Methods:

    • Eleven pregnant ewes were subjected to hyperbaric conditions equivalent to 165 feet of seawater.
    • Dives were conducted multiple times between days 112 and 137 of gestation.
    • Maternal and fetal circulations were monitored for bubble formation using external Doppler probes during decompression in 13 dives.

    Main Results:

    • Bubbles were detected in the maternal circulation of 8 out of 12 ewes.
    • No bubbles were detected in the fetal circulation of any ewe.
    • Nine ewes delivered normal lambs at term; one experienced fetal demise during labor, and another underwent cesarean section for examination.

    Conclusions:

    • Hyperbaric exposure can cause bubble formation in the maternal circulation of pregnant sheep.
    • Fetal circulation appears to be protected from bubble formation under these hyperbaric conditions.
    • The study suggests that hyperbaric dives may be relatively safe for fetal lambs regarding bubble-related complications.

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