Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Subungual keratoacanthoma

D M Stoll, A B Ackerman

    The American Journal of Dermatopathology
    |January 1, 1980
    PubMed
    Summary
    This summary is machine-generated.

    Subungual keratoacanthomas are rare but distinct from common keratoacanthomas. These distinct tumors are more destructive and do not regress spontaneously.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Nevoid basal cell carcinoma syndrome versus generalized basaloid follicular hamartoma syndrome.

    Journal of cutaneous pathology·2009
    Same author

    Some contentious questions.

    Journal of cosmetic dermatology·2006
    Same author

    A critique of the concept of healthy skin--and notions related to it.

    Journal of cosmetic dermatology·2006
    Same author

    Solar (actinic) keratosis is squamous cell carcinoma.

    The British journal of dermatology·2006
    Same author

    The future of pathology as a discipline: none without a dictionary!

    Ceskoslovenska patologie·2005
    Same author

    Sentinel node biopsy has no benefit for patients whose primary cutaneous melanoma has metastasized to a lymph node and therefore should be abandoned now.

    The British journal of dermatology·2004
    Same journal

    Herpetic Whitlow in Association With a Cutaneous Infiltrate of Chronic Lymphocytic Leukemia.

    The American Journal of dermatopathology·2026
    Same journal

    Basal Cell Carcinosarcoma with an Osteosarcomatous Component: A Case Report Supporting the Diagnostic Utility of SATB2 and TRAP Immunostaining with a Literature Review of 22 Cases.

    The American Journal of dermatopathology·2026
    Same journal

    Demonstration of 23-Gene Expression Profile Test Utility Within PRAME Immunohistochemistry Results: A Case Series.

    The American Journal of dermatopathology·2026
    Same journal

    On the Progression From Early-to Late-Stage Melanoma: A Potential Sequence of Molecular Events Using Data From Droplet Digital PCR and Array Comparative Genomic Hybridization, A Pilot Study.

    The American Journal of dermatopathology·2026
    Same journal

    Montgomery Tubercles in the Male Areola: Histological Observations and a Brief About Past Investigators.

    The American Journal of dermatopathology·2026
    Same journal

    Metastatic Syringocystadenocarcinoma Papilliferum Mimicking Cutaneous Squamous Cell Carcinoma of Unknown Primary in a Young Patient.

    The American Journal of dermatopathology·2026
    See all related articles

    Area of Science:

    • Dermatology
    • Oncology

    Background:

    • Keratoacanthomas are typically found on sun-exposed, hair-bearing skin.
    • Subungual keratoacanthomas are exceptionally rare, with limited documented cases.

    Observation:

    • This study critically reviews 12 previously reported cases and presents 2 new cases of subungual keratoacanthomas.
    • Histological analysis reveals distinct features differentiating subungual keratoacanthomas from those on hair-bearing skin.

    Findings:

    • Subungual keratoacanthomas exhibit unique clinical and histological characteristics, including similarity to verruca vulgaris, increased dyskeratotic cells, and a vertical growth orientation.
    • Unlike common keratoacanthomas, subungual variants show no spontaneous regression, have a prolonged course, and possess a propensity for bone destruction.
    • These tumors are paradoxically more destructive than subungual squamous cell carcinoma.

    Related Experiment Videos

    Implications:

    • Recognizing subungual keratoacanthoma as a distinct entity is crucial for accurate diagnosis and management.
    • The aggressive nature of subungual keratoacanthoma necessitates prompt and appropriate therapeutic intervention.
    • Further research into the pathogenesis and optimal treatment strategies for subungual keratoacanthoma is warranted.