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Updated: Aug 17, 2026

A Novel Approach for the Administration of Medications and Fluids in Emergency Scenarios and Settings
06:59

A Novel Approach for the Administration of Medications and Fluids in Emergency Scenarios and Settings

Published on: November 9, 2016

[Observations on preoperative restriction of fluid intake in infants (author's transl)]

G B Kraus

    Anasthesie, Intensivtherapie, Notfallmedizin
    |April 1, 1981
    PubMed

    Insights

    Reducing the interval between fluid intake and anesthesia to 4 hours appears safe for infants. Studies show that 10% glucose solution is almost completely emptied from the stomach within 4 hours, minimizing anesthetic risks.

    Area of Science:

    • Pediatric Anesthesiology
    • Gastrointestinal Physiology

    Context:

    • Investigating anesthetic risks associated with reduced fasting intervals in infants.
    • Evaluating gastric emptying times following fluid administration before anesthesia.

    Purpose:

    • To determine if a 4-hour fasting interval post-fluid intake increases anesthetic risks in infants.
    • To assess gastric residual volume, pH, and glucose concentration at different time points.

    Summary:

    • Gastric fluid volume, pH, and glucose were measured in 23 infants 6 hours after normal feeding and 2-4 hours after a 10% glucose solution feed.
    • Results indicated near-complete gastric emptying within 4 hours after administering a 10% glucose solution.

    Impact:

    • Provides evidence to potentially shorten pre-anesthetic fasting guidelines for infants.
    • Informs clinical practice regarding fluid management and anesthetic safety in pediatric patients.

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