Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Cutaneous eruptions in congenital tuberculosis

M K McCray, N B Esterly

    Archives of Dermatology
    |August 1, 1981
    PubMed
    Summary

    Two infants born to mothers with tuberculosis developed identical skin lesions. Diagnosis was confirmed via laparotomy, and both infants responded well to treatment, highlighting a rare presentation of systemic tuberculosis.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Congenital Volkmann ischaemic contracture: a case report and review.

    The British journal of dermatology·2004
    Same author

    Solitary, lobulated, firm nodule.

    Pediatric dermatology·2001
    Same author

    The spectrum of pathogenic mutations in SPINK5 in 19 families with Netherton syndrome: implications for mutation detection and first case of prenatal diagnosis.

    The Journal of investigative dermatology·2001
    Same author

    Drug-induced hypersensitivity syndrome in pediatric patients.

    Pediatrics·2001
    Same author

    Hypersensitivity syndromes.

    Adolescent medicine (Philadelphia, Pa.)·2001
    Same author

    Vesiculopustular eruptions in Down syndrome neonates with myeloproliferative disorders.

    Archives of dermatology·2001

    Area of Science:

    • Dermatology
    • Pediatrics
    • Infectious Diseases

    Background:

    • Systemic tuberculosis (TB) can present with diverse clinical manifestations.
    • Congenital tuberculosis, transmitted from mother to infant, poses diagnostic challenges.
    • Cutaneous manifestations of tuberculosis in infants are uncommon and require careful evaluation.

    Observation:

    • Two infants born to mothers with active tuberculosis developed similar skin lesions.
    • Erythematous papules with central crusted dells appeared at 4 and 8 weeks postpartum.
    • Mycobacterium tuberculosis was not identified in the skin lesions themselves.

    Findings:

    • Diagnosis of systemic tuberculosis was confirmed through tissue examination during laparotomy.
    • The infants' conditions showed significant improvement with standard antituberculous therapy.
    • The specific categorization of these infant skin lesions in relation to systemic TB is discussed.

    Implications:

    • This case series underscores the importance of considering systemic tuberculosis in infants presenting with unexplained skin lesions.
    • Early diagnosis and treatment of congenital TB are crucial for favorable outcomes.
    • Further research into the pathogenesis and classification of TB-associated dermatoses in neonates is warranted.

    Related Experiment Videos