Verruciform xanthoma of the penis

We describe herein a patient with a verruciform xanthoma of the penis. This histologically distinctive lesion is usually confined to the oral mucosa, although two cases occurring on the vulva have recently been reported. To our knowledge, this lesion has not been previously described in other sites. Biopsy for histopathologic examination is required to aid in the identification of this unusual entity. Verruciform xanthomas have been benign, although a squamous cell carcinoma subsequently developed in one patient whose oral lesions were associated with leukoplakia.