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Related Experiment Videos

A polymorph bactericidal defect and a lupus-like syndrome

R J Levinsky, B A Harvey, D M Roberton

    Archives of Disease in Childhood
    |May 1, 1981
    PubMed
    Summary
    This summary is machine-generated.

    This study details a child with impaired bacterial killing and systemic lupus erythematosus. Researchers propose chronic bacterial exposure may trigger autoimmune disease in individuals with immunodeficiency.

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    The Fc receptor for IgG (Fc gamma RII; CD32) on human neonatal B lymphocytes.

    Human immunology·2001

    Area of Science:

    • Immunology
    • Pediatrics
    • Rheumatology

    Background:

    • Primary immunodeficiencies can manifest with diverse clinical symptoms.
    • Autoimmune diseases, such as systemic lupus erythematosus (SLE), involve immune system dysregulation.
    • The interplay between infection, immunity, and autoimmunity is complex and not fully understood.