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Necrotising enterocolitis in older infants

K Takayanagi, L Kapila

    Archives of Disease in Childhood
    |June 1, 1981
    PubMed
    Summary

    Necrotising enterocolitis (NEC) can affect children beyond the neonatal period. This severe gastrointestinal illness may develop after gastroenteritis, even in older infants and toddlers.

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    Area of Science:

    • Pediatric Gastroenterology
    • Neonatal Medicine
    • Surgical Gastroenterology

    Background:

    • Necrotising enterocolitis (NEC) is a serious intestinal condition typically affecting newborns.
    • The established understanding of NEC primarily focuses on the neonatal intensive care unit population.

    Observation:

    • A study observed thirteen pediatric patients, aged 45 days to 2 years, presenting with severe gastrointestinal distress.
    • These children exhibited clinical features strongly indicative of necrotising enterocolitis.
    • All patients had a history of preceding gastroenteritis, which led to hypovolemia.

    Findings:

    • Necrotising enterocolitis (NEC) is not exclusively a neonatal condition.
    • The findings indicate that NEC can manifest in infants and young children beyond the typical neonatal age range.
    • Gastroenteritis followed by hypovolemia appears to be a significant precursor in these non-neonatal cases.

    Implications:

    • Clinical awareness of NEC should extend beyond the neonatal period.
    • Pediatricians and gastroenterologists should consider NEC in older infants and toddlers with severe gastrointestinal symptoms post-gastroenteritis.
    • Further research is warranted to understand the pathophysiology and optimal management of non-neonatal NEC.

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