Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Wound contraction. A quantitative interpretation

J M Snowden

    The Australian Journal of Experimental Biology and Medical Science
    |April 1, 1981
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Hospital variation in costs - a challenge to the value proposition.

    BJOG : an international journal of obstetrics and gynaecology·2017
    Same author

    Causal inference in studies of preterm babies: a simulation study.

    BJOG : an international journal of obstetrics and gynaecology·2017
    Same author

    Outcomes of flu in pregnancy: summarizing what is known.

    BJOG : an international journal of obstetrics and gynaecology·2016
    Same author

    Term elective induction of labour and perinatal outcomes in obese women: retrospective cohort study.

    BJOG : an international journal of obstetrics and gynaecology·2016
    Same author

    Trends in the HIV Epidemic Among African American Men Who Have Sex with Men, San Francisco, 2004-2011.

    AIDS and behavior·2015
    Same author

    Studying and preventing stillbirth: what are the methodological issues?

    Journal of perinatology : official journal of the California Perinatal Association·2012
    Same journal

    The effect of cyanide and carbon monoxide on the oxygen consumption of Paramoecium caudatum.

    The Australian journal of experimental biology and medical science·2010
    Same journal

    The quantitative extraction of cobalt and iron from ashed biological material.

    The Australian journal of experimental biology and medical science·2010
    Same journal

    Studies in the metabolism of plant cells; the reversibility of the salt respiration.

    The Australian journal of experimental biology and medical science·2010
    Same journal

    The effect of intake of carotene on the general health and on the concentration of carotene and of vitamin A in the blood and liver of sheep.

    The Australian journal of experimental biology and medical science·2010
    Same journal

    The vitamin C content of dried lucerne (Medicago sativa): chemical and biological assays.

    The Australian journal of experimental biology and medical science·2010
    Same journal

    The determination of vitamin C by the growth of guinea-pigs.

    The Australian journal of experimental biology and medical science·2010
    See all related articles

    Wound contraction in various species follows a consistent linear rate of margin movement. This rate, calculable from wound area over time, is key for comparing healing speeds.

    Area of Science:

    • Wound healing research
    • Comparative physiology
    • Tissue regeneration

    Background:

    • Excisional wounds are common injuries requiring effective healing.
    • Understanding wound contraction dynamics is crucial for therapeutic development.
    • Previous studies have explored wound healing but lacked a standardized quantitative measure for contraction rates.

    Purpose of the Study:

    • To analyze the behavior of dressed excisional wounds across multiple species.
    • To identify a reliable parameter for quantifying the rate of wound contraction.
    • To establish a method for comparing contraction rates between different species and conditions.

    Main Methods:

    • Analysis of excisional wound behavior in humans, rabbits, rats, and mice.
    • Measurement of wound area changes over time.

    Related Experiment Videos

  • Mathematical modeling to correlate wound area change with time.
  • Graphical analysis using (area)1/2 versus time plots.

    • Main Results:

    • Wound contraction in all studied species demonstrated a constant linear rate of wound margin movement.
    • The rate of wound margin movement was found to be a suitable parameter for quantitative comparison.
    • The parameter for contraction rate can be accurately determined from the slope of (area)1/2 versus time plots.

    Conclusions:

    • The linear rate of wound margin movement is a consistent and quantifiable aspect of excisional wound healing.
    • This parameter provides a standardized method for comparing wound contraction efficacy across species.
    • The (area)1/2 versus time plot offers a practical tool for assessing wound healing dynamics.