Feather lesions in cyclophosphamide-treated chickens

One-day-old White Leghorn chickens each treated with 4 mg of cyclophosphamide for 3 consecutive days developed feather lesions 4 days after treatment. The lesions were characterized by short feathers with an absence of barbs mainly in the proximal portion and sometimes in the mid- or distal portion of the rachis. The lesions disappeared when the chickens were 4 weeks old.