[Ribosomal crystallization in the in vitro differentiation of mesenchymal cells interacting with the epithelium]

Ribosomal crystallization of 6-day chick embryo thigh skin in vitro in two different nutrient media was studied. The embryo thigh skin has been incubated for 3 or 6 days in media containing either chick embryo extract or chick serum, than submitted to hypothermia for 36 hours to induce the formation of ribosome crystals. The crystals are present in almost all type of cells in E medium, while in the cells in CS medium only after 3 days; therefore it is possible to relate the crystallization with the different degree of differentiation attained in mesenchymal cells.