Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Subacute massive pulmonary embolism

R J Hall, D McHaffie, C Pusey

    British Heart Journal
    |June 1, 1981
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Glomerular endothelial derived vesicles mediate podocyte dysfunction: A potential role for miRNA.

    PloS one·2020
    Same author

    Prognosis and future developments in vasculitis.

    Best practice & research. Clinical rheumatology·2018
    Same author

    A dosimetric analysis of tomotherapy based intensity modulated radiation therapy with and without bone marrow sparing in gynecologic malignancies.

    Technology in cancer research & treatment·2012
    Same author

    Newly diagnosed heart failure: change in quality of life, mood, and illness beliefs in the first 6 months after diagnosis.

    British journal of health psychology·2011
    Same author

    Experience of using human albumin solution 4.5% in 1195 therapeutic plasma exchange procedures.

    Transfusion medicine (Oxford, England)·2010
    Same author

    Improving survival in the 6 months after diagnosis of heart failure in the past decade: population-based data from the UK.

    Heart (British Cardiac Society)·2009
    Same journal

    Cardiac enlargement with bradycardia in recruits.

    British heart journal·2010
    Same journal

    Paravertebral block and the electrocardiogram in angina pectoris.

    British heart journal·2010
    Same journal

    Induced changes in the circulation in constrictive pericarditis.

    British heart journal·2010
    Same journal

    Angina pectoris with associated left paroxysmal ptosis.

    British heart journal·2010
    Same journal

    Myxoedema with pericardial effusion.

    British heart journal·2010
    Same journal

    Hypoxaemia tests in coronary disease.

    British heart journal·2010
    See all related articles

    Subacute massive pulmonary embolism presents with progressive dyspnea. While early treatment response varied, long-term outcomes were favorable, with no evidence of recurrent disease or late pulmonary hypertension.

    Area of Science:

    • Cardiology
    • Pulmonary Medicine
    • Vascular Surgery

    Background:

    • Subacute massive pulmonary embolism (MPE) is a serious condition often presenting with prolonged dyspnea.
    • Clinical signs may indicate right heart strain and ventilation/perfusion mismatch.
    • Diagnostic imaging like chest X-ray and electrocardiogram can provide valuable, though sometimes normal, findings.

    Purpose of the Study:

    • To investigate the clinical presentation, treatment response, and long-term outcomes of patients with subacute massive pulmonary embolism.
    • To assess the potential for recurrent embolic disease and late pulmonary hypertension following subacute MPE.

    Main Methods:

    • Prospective study of 24 patients with subacute MPE.
    • Clinical evaluation during initial illness and follow-up up to nine years.

    Related Experiment Videos

  • Assessment of treatment response to thrombolysis, heparin, and pulmonary embolectomy.

    • Main Results:

    • Progressive dyspnea over weeks was the most common presentation.
    • Early thrombolytic treatment response was generally poor compared to acute MPE.
    • Heparin monotherapy was effective in eight patients; pulmonary embolectomy yielded poor results with high mortality.
    • Nine patients died during the initial illness, seven due to embolic disease.

    Conclusions:

    • Subacute MPE has a prolonged course with variable treatment responses.
    • Despite initial severity, long-term follow-up showed no evidence of recurrent disease or late pulmonary hypertension.
    • Heparin appears to be a satisfactory treatment option, while pulmonary embolectomy is associated with poor outcomes.