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Related Experiment Videos

The fellow eye

R Mapstone

    The British Journal of Ophthalmology
    |June 1, 1981
    PubMed
    Summary
    This summary is machine-generated.

    Routine iridectomy is often unnecessary for preventing closed-angle glaucoma in the fellow eye. Most glaucoma cases develop within six months, and many eyes can be monitored without surgery.

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    Area of Science:

    • Ophthalmology
    • Glaucoma Research
    • Longitudinal Studies

    Background:

    • Closed-angle glaucoma (CAG) poses a risk to the fellow eye when one eye is already affected.
    • Prophylactic interventions like iridectomy have been considered to prevent CAG in at-risk fellow eyes.

    Purpose of the Study:

    • To evaluate the long-term outcomes of monitoring fellow eyes at risk for closed-angle glaucoma.
    • To determine the necessity and efficacy of routine iridectomy in preventing CAG in the fellow eye.

    Main Methods:

    • A 10-year longitudinal study observed 202 fellow eyes at risk for CAG.
    • Eyes underwent provocative testing (pilocarpine-phenylephrine); iridectomy was performed if CAG was induced.
    • Eyes without induced CAG were observed and re-tested annually.

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    Main Results:

    • 90% of acute CAG attacks occurred within 6 months of initial presentation.
    • The cumulative probability of surviving 5 years without CAG was 0.34 (34%), suggesting many iridectomies were unnecessary.
    • Ocular hypertension was prevalent (26%) in untreated fellow eyes that did not develop CAG.

    Conclusions:

    • Routine iridectomy is not necessary for all fellow eyes at risk of CAG.
    • The development of CAG in the fellow eye can often be predicted, allowing for targeted monitoring.
    • Untreated fellow eyes serve as a model for studying ocular hypertension mechanisms.