[Potentiodynamic method of studying the reaction between liposomes and bilayer lipid membranes]

Changes of surface potential difference of neutral BLM in the presence of negatively charged liposomes were controlled by means of potentiodynamic method. The liposomes were prepared by sonication of PS-suspension in buffer solution. BLM was formed conventionally from lecithin--decane mixture. Measurements were carried out in buffer solution 2 mM KCL, 5 mM Tris-Cl pH 7.6) at 30 degrees C. It is shown that the liposomes are irreversibly bound to BLM, but do not fuse with it under the conditions investigated.