[Correlation between [NAD+]:[NADH] and the "phosphate potential" in liver cytoplasm of developing chicken embryos]

No correlation between the changes in the ratios of [NAD+]:[NADH] and [ATP]/[ADP] . [HPO4(2-)] in liver cytoplasm of developing chicken embryos was found. The [ATP]/[ADP] . [HPO4(2-)] ratio depends on the rate of gluconeogenesis. The [NAD+]:[NADH] ratio remains unchanged up to hatching and is then decreased 2-fold, the [ATP]/[ADP] . [HPO4(2-)] ratio being unchanged. The experimental and theoretical values of the "phosphate potential" show a coincidence.