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Thyroid function screening in psychiatric in-patients

M W Carney, S Macleod, B F Sheffield

    The British Journal of Psychiatry : the Journal of Mental Science
    |February 1, 1981
    PubMed
    Summary
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    Thyroid dysfunction was found in 20% of psychiatric admissions. While linked to certain factors, it was not the primary cause of psychiatric disturbance in most cases.

    Area of Science:

    • Endocrinology
    • Psychiatry
    • Biochemistry

    Background:

    • Thyroid disease is common and can manifest with psychiatric symptoms.
    • Screening for thyroid dysfunction in psychiatric populations is important for diagnosis and treatment.

    Purpose of the Study:

    • To determine the prevalence of thyroid dysfunction in psychiatric admissions.
    • To investigate the association between thyroid dysfunction and psychiatric diagnoses, patient demographics, and medication use.

    Main Methods:

    • A two-year biochemical screening was conducted on 191 psychiatric admissions.
    • Thyroid function tests were analyzed.
    • Patient demographics, psychiatric diagnoses, and medication history were recorded.

    Main Results:

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    • 20% of patients (38 out of 191) had abnormal thyroid function results (5 hyperthyroid, 7 hypothyroid).
    • Thyroid dysfunction was associated with female sex and affective psychosis, but not age.
    • Patients with abnormal thyroid function had higher rates of phenothiazine, antiparkinsonian, and lithium use prior to admission.
    • Nearly half of those with abnormal thyroid function were physically ill upon admission.

    Conclusions:

    • Thyroid dysfunction is relatively common in psychiatric admissions.
    • While associated with specific patient characteristics and medication use, thyroid dysfunction was not found to be the main driver of psychiatric disturbance in the majority of patients studied.