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Published on: August 14, 2015
Modulation of harmaline-induced rhythmic discharge of the inferior olive by juxtafastigial stimulation
We previously reported induction or suppression by juxtafastigial stimulation of the rhythmic complex spike discharge of Purkinje cells in harmaline treated rats. In this paper we show that this modulation of the cerebellar rhythmic activity implies the involvement of inferior olive neurons. These results are discussed in the general framework of the olivo-cerebello-bulbar circuitry. A modulatory control of the inferior olive neuron activity by the raphe system is suggested to explain part of these results.
We previously reported induction or suppression by juxtafastigial stimulation of the rhythmic complex spike discharge of Purkinje cells in harmaline treated rats. In this paper we show that this modulation of the cerebellar rhythmic activity implies the involvement of inferior olive neurons. These results are discussed in the general framework of the olivo-cerebello-bulbar circuitry. A modulatory control of the inferior olive neuron activity by the raphe system is suggested to explain part of these results.
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