Modulation of harmaline-induced rhythmic discharge of the inferior olive by juxtafastigial stimulation

Brain Research
|June 29, 1981
PubMed

We previously reported induction or suppression by juxtafastigial stimulation of the rhythmic complex spike discharge of Purkinje cells in harmaline treated rats. In this paper we show that this modulation of the cerebellar rhythmic activity implies the involvement of inferior olive neurons. These results are discussed in the general framework of the olivo-cerebello-bulbar circuitry. A modulatory control of the inferior olive neuron activity by the raphe system is suggested to explain part of these results.