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Updated: Aug 16, 2026

The MODS method for diagnosis of tuberculosis and multidrug resistant tuberculosis
Published on: August 11, 2008
A second study of the use of community leaders in case-finding for pulmonary tuberculosis in Kenya
Abstract:
This is the second study of case-finding activities for tuberculosis suspects undertaken in 2 locations of Machakos District. Three methods were investigated, namely (1) the requestioning of the Community Elders 1 year or more after a first questioning in the original study, (2) the examination of patients registered in the District Tuberculosis Register from 1969--1974 and (3) the examination of their close contacts. Requestioning the Elders produced a total of 421 suspects, 129 (31%) of whom had not been identified a year previously. The yield of freshly identified smear-positive, culture-positive cases was 0.7 per 100 suspects examined and of all culture-positive cases was 1.7. However, all the smear-positive and 1.0 per 100 of the culture-positive cases were old patients who had previously been registered in the District Tuberculosis Register. Of the 181 patients with tuberculosis in the Register bacteriological results were available for 97; of these 6 were smear-positive, 9 culture-positive--yields of 6.2 smear-positive, culture-positive cases per 100 registered persons examined. The corresponding yields for the 63 persons who had been registered as having pulmonary disease were 9.5 and 14.3. Of the 9 culture-positive, 7 had strains resistant to isoniazid, but all were sensitive to streptomycin. The examination of the 628 close contacts of the registered patients produced only 3 culture-positive cases, none of whom was smear-positive--a yield of 0.5 culture-positive cases per 100 contacts examined. All 3 strains were sensitive to isoniazid and streptomycin.
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