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N-acetyl-L-leucine for Niemann-Pick type C: a multinational double-blind randomized placebo-controlled crossover study.

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A master protocol to investigate a novel therapy acetyl-L-leucine for three ultra-rare neurodegenerative diseases: Niemann-Pick type C, the GM2 gangliosidoses, and ataxia telangiectasia.

Trials·2021

Quality of life improvement in older patients with heart failure initiated on ivabradine: Results from the UK multi-centre LIVE:LIFE prospective cohort study.

International journal of cardiology·2017

Combination treatment with mirabegron and solifenacin in patients with overactive bladder: exploratory responder analyses of efficacy and evaluation of patient-reported outcomes from a randomized, double-blind, factorial, dose-ranging, Phase II study (SYMPHONY).

World journal of urology·2016

The analysis of incontinence episodes and other count data in patients with overactive bladder by Poisson and negative binomial regression.

Pharmaceutical statistics·2014

YAP1-Driven PLCβ1 Impairs MHC-I Antigen Presentation and Limits Anti-Tumor Immunity in Gastrointestinal Cancer.

Cancer research·2026

Exercise modulates microbial metabolites and induces stromal remodeling in pancreatic cancer.

Cancer research·2026

Mathematical and Mouse Models Identify Regulatory T Cell Influx as A Key Determinant of Acquired Resistance to PD-1 Immunotherapy.

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The Multimodal Pretraining Framework CarHE Predicts Spatial Transcriptomics in Tumors from Routine Pathology Images.

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Transcriptomic Profiling of Mouse Mammary Tumors Enables Prognostic and Predictive Biomarker Discovery for Human Breast Cancer.

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RASA2 Promotes Pancreatic Cancer Metastasis by Activating TGFβ-Dependent Non-canonical Hedgehog Signaling.

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Opportunistic Screening for Bone Demineralization by Whole Body CT in a Red-Handed Howler Monkey (Alouatta belzebul) Under Human Care.

Journal of medical primatology·2026

Association of Body Fluid Distribution with Bone Mineral Density and Osteoporosis in Men Aged under 50: A Cross-Sectional Study.

The American journal of the medical sciences·2026

[Evaluation of analytical transferability between two methods for measuring serum iron levels using Ferrozine and Ferene S].

Annales de biologie clinique·2026

Urolithins in clinical translation: from gut microbial metabolites to precision interventions.

Frontiers in nutrition·2026

Mitochondrial dysfunction in intracerebral hemorrhage: molecular mechanisms and pathological consequences.

Frontiers in cellular neuroscience·2026

[Еxosomes: possibilities and prospects in the diagnosis and treatment of digestive diseases].

Terapevticheskii arkhiv·2026

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Working Group III: lipid metabolites and intestinal flora. Introduction

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N-acetyl-L-leucine for Niemann-Pick type C: a multinational double-blind randomized placebo-controlled crossover study.

A master protocol to investigate a novel therapy acetyl-L-leucine for three ultra-rare neurodegenerative diseases: Niemann-Pick type C, the GM2 gangliosidoses, and ataxia telangiectasia.

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