Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Proplast and Plastipore

A G Kerr

    Clinical Otolaryngology and Allied Sciences
    |June 1, 1981
    PubMed
    Summary
    This summary is machine-generated.

    Histological analysis of explanted Proplast and Plastipore prostheses revealed fibrous capsule formation. Proplast showed fibrous tissue ingrowth, unlike Plastipore, with both exhibiting foreign body giant cells and signs of material breakdown.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Long-term changes in adipose tissue gene expression following bariatric surgery.

    Journal of internal medicine·2020
    Same author

    Epigenetic regulation of diabetogenic adipose morphology.

    Molecular metabolism·2019
    Same author

    British CME: a framework for the future.

    Journal of the Royal Society of Medicine·2010
    Same author

    Prevention of occupational transmission of HIV in the ENT clinic: Assessor's comment.

    Annals of the Royal College of Surgeons of England·2009
    Same author

    Assessment of vertigo.

    Annals of the Academy of Medicine, Singapore·2005
    Same author

    Management of otoscierosis--an Irish perspective.

    Irish medical journal·2002
    Same journal

    Correspondence.

    Clinical otolaryngology and allied sciences·2017
    Same journal

    Erratum.

    Clinical otolaryngology and allied sciences·2013
    Same journal

    Compact training course in ear surgery erlangen, Germany, 26-28 february 1998.

    Clinical otolaryngology and allied sciences·2013
    Same journal

    How we do it: a practical approach to Foley catheter posterior nasal packing.

    Clinical otolaryngology and allied sciences·2004
    Same journal

    How we do it: management of tracheobronchial foreign bodies in children.

    Clinical otolaryngology and allied sciences·2004
    Same journal

    Is cochlear outer hair cell function affected by mobile telephone radiation?

    Clinical otolaryngology and allied sciences·2004
    See all related articles

    Area of Science:

    • Biomaterials Science
    • Orthopedic Surgery
    • Histopathology

    Background:

    • Prosthetic implants are utilized in reconstructive surgery to restore function.
    • The long-term integration and stability of porous implant materials are critical for clinical success.
    • Understanding the host tissue response to different biomaterials is essential for improving implant design.

    Purpose of the Study:

    • To histologically evaluate the tissue response and material integrity of explanted Proplast and Plastipore prostheses.
    • To compare the fibrous tissue ingrowth and cellular reactions between Proplast and Plastipore implants.
    • To identify potential causes of failure or degradation in these commonly used prostheses.

    Main Methods:

    • Histological examination of 16 Proplast and 52 Plastipore prostheses retrieved during revision surgery.

    Related Experiment Videos

  • Macroscopic assessment of implant appearance and surrounding fibrous tissue.
  • Microscopic analysis for fibrous tissue ingrowth, cellular infiltration (including giant cells), and signs of material degradation.

    • Main Results:

    • Macroscopic appearance of prostheses was generally preserved.
    • Common finding of fibrous tissue capsule formation around both implant types.
    • Consistent fibrous tissue ingrowth observed in Proplast, but not in Plastipore prostheses.
    • Large numbers of multinucleated foreign body giant cells were present in both Proplast and Plastipore.
    • Histological evidence indicated breakdown and degradation of both types of prostheses.

    Conclusions:

    • Proplast demonstrates better fibrous tissue integration compared to Plastipore, suggesting potential for improved mechanical stabilization.
    • The presence of foreign body giant cells and material breakdown in both implant types highlights potential long-term biocompatibility and durability concerns.
    • Further research is needed to optimize porous biomaterials for enhanced osseointegration and reduced degradation in orthopedic applications.