Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

APACHE-acute physiology and chronic health evaluation: a physiologically based classification system

W A Knaus, J E Zimmerman, D P Wagner

    Critical Care Medicine
    |August 1, 1981
    PubMed
    Summary

    A new classification system, APACHE (Acute Physiology and Chronic Health Evaluation), reliably measures illness severity in intensive care units (ICUs). This tool aids in comparing patient outcomes and evaluating therapies.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Health Heritage© a web-based tool for the collection and assessment of family health history: initial user experience and analytic validity.

    Public health genomics·2010
    Same author

    Antibiotics for severe chronic obstructive pulmonary disease.

    Lancet (London, England)·2002
    Same author

    Comparison of the performance of two comorbidity measures, with and without information from prior hospitalizations.

    Medical care·2001
    Same author

    Cannot draw generic conclusions from a single study.

    Critical care medicine·2001
    Same author

    The importance of bacterial sepsis in intensive care unit patients with acquired immunodeficiency syndrome: implications for future care in the age of increasing antiretroviral resistance.

    Critical care medicine·2001
    Same author

    Intensive care unit length of stay: recent changes and future challenges.

    Critical care medicine·2000

    Area of Science:

    • Critical Care Medicine
    • Health Services Research

    Background:

    • Limited reliable systems exist for classifying intensive care unit (ICU) patient severity.
    • Accurate patient classification is crucial for understanding ICU utilization and value.

    Purpose of the Study:

    • To develop and validate the Acute Physiology and Chronic Health Evaluation (APACHE) system.
    • To establish a physiologically based measure for critically ill patient severity.

    Main Methods:

    • Developed APACHE using medical record data.
    • Conducted reliability and validation studies on 805 ICU admissions across two hospitals.
    • Employed sensitivity analyses for diverse patient groups.

    Main Results:

    • APACHE demonstrated reliability in classifying ICU admissions.

    Related Experiment Videos

  • The acute physiology score showed consistent agreement with therapeutic effort and mortality.
  • Validation held across various patient cohorts.

    • Conclusions:

    • APACHE is a reliable system for measuring illness severity in critically ill patients.
    • The system can be utilized for case mix control, outcome comparison, and therapy evaluation.
    • Further multi-institutional validation is recommended for broader application.