Schilder's disease. A study of the cerebral cortex with Golgi's method

The cerebral cortex of a patient with Schilder's disease was studied with the Golgi method. The number of synaptic spines, basal dendrites, branching points, and dendritic intersection points of 5th layer pyramids are similar to those of controls, in spite of almost complete loss of extrinsic fibers. These data illustrate the probable remodeling of intrinsic cortical circuits and neuronal plasticity in the human cerebral cortex.