Histologic and cytologic studies on atypical epithelial growth of the stomach

Thirty three resected gastric lesions were examined histologically to analyze the relationship between histologic and cytologic diagnoses of the so-called atypical epithelial growth based on biopsy specimens. Of the 33 lesions twenty were histologically verified atypical epithelial growth and the remaining thirteen were, in the same manner, diagnosed with some equivocation as papillary adenocarcinoma. The results of both histological and cytological diagnoses of the biopsy materials from the above mentioned 33 lesions were as follows; for the twenty atypical epithelial growths, 18 were diagnosed as benign, one was as suspicious of malignancy and the other one was as cancer by biopsy histology, whereas these lesions were diagnosed as benign in 16, suspicious in two and cancer in two by cytology; for the thirteen papillary adenocarcinoma, 8 were diagnosed as benign, 4 were as suspicious of malignancy and one was as cancer by biopsy histology. On the other hand their diagnoses were malignant in six, suspicious of cancer in four and benign in three by biopsy cytology. The data indicate that biopsy cytology favors malignancy for atypical epithelial growth and papillary adenocarcinoma when compared with biopsy histology.